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抗日战争时期，年轻的女考古学家方志珍与父亲方教授同在大学任教，志珍怀着强烈的爱国心决心把失落民间的神医华佗的医著寻找回来。志珍和日本考古学家川多磨在一座古塔中发现两颗明珠，却被也来寻书的德国人干戈一伙抢走，不久，川多磨奉命回国前夕，突然被指令留下寻找华佗医书，并有浪人西协美知子和高城丈二相助。干戈利诱大学教授携手寻书，志珍被他的无耻行径激怒，为尽快找到医书，她们来到漆黑的秘宫，在一颗明珠上找到了线索。她们立即赶到陈教授家，在一幅于禁跪送华佗的画里找到了“开启天门之匙”的字样。干戈随后而至，字迹已被志珍抹去。火车站上，志珍与川多磨相遇。川多磨直言相告，志珍更坚定了保住国宝的决心。她蓦然想起老同学蓝天曾说过家有宝物，是两把“开启天门之匙”。她与川多磨找到蓝天，蓝天慨然相赠，不料干戈的爪牙白痴突然将钥匙抢走，争斗中，白痴摔倒在炉旁石头上，烫热的钥匙在他前额...。Katherine of Alexandria, brought up as a nomad and living in the desert, was aged just 11 when Emperor Maxentius saw her whilst out on patrol. Consumed by her beauty, impudence and uncanny talent for languages, he abducted the child, killing her family. The slaughter was witnessed by her young friend, Constantine, who would later become Emperor of the Western Roman Empire. He never lost hope of finding Katherine. As a young woman, Katherine refused to submit to Maxentius' offers of marriage and she continually denounced his brutal enforcement of pagan religion upon the masses. Still obsessed with her beauty, Maxentius brought Katherine before 50 of Rome's finest scholars in an open court in Alexandria, where she eloquently demolished their arguments. When Constantine learned of Katherine's whereabouts and imprisonment at the hands of Maxentius, he led his army from York in a desperate bid to save her.。道光年间，西林春 (胡静 饰)的父亲鄂硕因不愿参与宠妃全妃的后宫之争而惨遭迫害，西林春为了替父亲讨回公道而决定入京参加选秀。克服了母亲的重重阻挠而在进京赶考的安雪臣(黄维德 饰)的帮助下进入皇宫的西林春却不想自己已被从秀女名单上除名，而她更是因为不小心卷入全妃(傅艺伟 饰)和祥嫔(伊能静 饰)的权利之争而被发配辛者库，开始了艰苦的奴隶生活。为了报仇西林春开始了步步为营的隐忍计划，更是在这场纷杂的宫廷之争中结识了各自肩负使命入宫的景珍(陈炜 饰)，兰轩(陈秀丽 饰)，三人虽各怀心思却结成了好姐妹。而就在西林春一步步的实行着自己的计划，自己又陷入了与荣广海(陈浩民 饰)，安雪臣三人的纠葛感情之中。就这样，众人就在这场勾心斗角的后宫生活中为了各自的目的挣扎的生存着。。